The moral universe inhabited by the characters of the 4400 is complex at the best of times, and the clip you have just seen (taken from the closing minutes of the finale of the show’s fourth season aired September 16, 2007), demonstrates how this moral ambiguity permeates not only the interaction between the fictional National Threat Assessment Center (NTAC) and “the 4400” returnees, but also relationships within families and between significant others, even those not necessarily involved in the central struggles of the show’s narrative. The danger posed by the defection of NTAC agents to Promicin advocates and “the 4400” at the beginning of the clip, is but one manifestation of the unpredictability and ubiquity of the sense of existential threat which pervades this series. Another interesting aspect of this clip is the fatigue and alienation that the costs of the struggle impose upon the NTAC agents. The agents and “the 4400” are commonly represented as having moments of indecision and lack of commitment to the struggle. In the 4400 the levels of alienation are portrayed as creating extreme moral fatigue in the agents, demonstrated in the penultimate segment of the clip when Agent Baldwin contemplates taking the Promicin shot offered to him by his son Kyle (and one of “the 4400”, an intimate materialization of threat that offers no refuge. Is the pervasiveness and intimacy of existential threat in the 4400 the manifestation of some unique historical discontinuity in the shadow of 9/11, or representation of a sense of alienation that has much deeper cultural and historical roots?